ATAD2 antibody (AA 1025-1063) (HRP)

Catalog No. ABIN1418770

This Rabbit Polyclonal antibody specifically detects ATAD2 in IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ATAD2 antibody (AA 1025-1063) (HRP) (ABIN1418770)

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATAD2 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ATAD2 Antibody (HRP)

Binding Specificity: AA 1025-1063

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATAD2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ATAD2

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Alternative Name: ATAD2

Background:

Synonyms: ANCCA, CT137, PRO2000, ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated protein, ATAD2, L16

Background: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.

Gene ID: 29028

UniProt: Q6PL18