ZNRF3 antibody (AA 120-165) (Cy3)
Quick Overview for ZNRF3 antibody (AA 120-165) (Cy3) (ABIN1418939)
Target
See all ZNRF3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 120-165
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human ZNRF3
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Isotype
- IgG
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anti-Zinc and Ring Finger Protein 3 (ZNRF3) (AA 56-219) antibody
ZNRF3 Reactivity: Human ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Zinc and Ring Finger Protein 3 (ZNRF3) (AA 120-165) antibodyZNRF3 Reactivity: Human, Mouse, Rat IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
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Application Notes
- IF(IHC-P) 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
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Alternative Name
- ZNRF3
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Background
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Synonyms: RNF203, BK747E2.3, E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133
Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
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Gene ID
- 84133
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UniProt
- Q9ULT6
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Pathways
- WNT Signaling
Target
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