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ZNRF3 antibody (AA 56-219) (Biotin)

ZNRF3 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7151319
  • Target See all ZNRF3 Antibodies
    ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
    Binding Specificity
    • 15
    • 4
    • 1
    • 1
    AA 56-219
    Reactivity
    • 23
    • 18
    • 16
    Human
    Host
    • 23
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZNRF3 antibody is conjugated to Biotin
    Application
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human E3 ubiquitin-protein ligase ZNRF3 protein (56-219AA)
    Isotype
    IgG
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
    Alternative Name
    ZNRF3 (ZNRF3 Products)
    Synonyms
    BK747E2.3 antibody, RNF203 antibody, AA591877 antibody, BC019575 antibody, Gm1167 antibody, zinc and ring finger 3 antibody, Znrf3 antibody, ZNRF3 antibody
    Background

    Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

    Aliases: ZNRF3 antibody, KIAA1133 antibody, RNF203 antibody, E3 ubiquitin-protein ligase ZNRF3 antibody, EC 2.3.2.27 antibody, RING finger protein 203 antibody, RING-type E3 ubiquitin transferase ZNRF3 antibody, Zinc/RING finger protein 3 antibody

    UniProt
    Q9ULT6
    Pathways
    WNT Signaling
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