MARCH4 antibody (HRP)
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- Target See all MARCH4 Antibodies
- MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MARCH4 antibody is conjugated to HRP
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MARCH4
- Isotype
- IgG
- Top Product
- Discover our top product MARCH4 Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))
- Alternative Name
- MARCH4 (MARCH4 Products)
- Synonyms
- MARCH-IV antibody, RNF174 antibody, BC056494 antibody, mKIAA1399 antibody, MARCH4 antibody, si:ch211-239d11.2 antibody, membrane associated ring-CH-type finger 4 antibody, membrane-associated ring finger (C3HC4) 4 antibody, MARCH4 antibody, March4 antibody, march4 antibody
- Background
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Synonyms: E3 ubiquitin protein ligase MARCH4, RNF174, KIAA1399, MARCH 4, MARCH IV, Membrane associated RING CH protein IV, Membrane associated ring finger C3HC4 4, Membrane associated RING finger protein 4, mKIAA1399, RING finger protein 174, MARH4_HUMAN.
Background: MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
- Gene ID
- 57574
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