PSMA2 antibody (HRP)

Catalog No. ABIN1420096

This Rabbit Polyclonal antibody specifically detects PSMA2 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PSMA2 antibody (HRP) (ABIN1420096)

Target: PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PSMA2 Antibody (HRP)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PSMA2

Target: PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

Background:

Synonyms: 20S Proteasome 2, HC3, Macropain subunit C3, MU antibody Multicatalytic endopeptidase complex subunit C3, PMSA2, Proteasome prosome macropain subunit alpha type 2, Proteasome alpha 2 subunit, Proteasome component C3, Proteasome subunit alpha type 2, Proteasome subunit alpha type-2, Proteasome subunit HC3, PSC2, PSC3, PSMA 2, psmA2, PSA2_HUMAN.

Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation.

Gene ID: 5683

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA