HEXIM1 antibody (Cy5)
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- Target See all HEXIM1 Antibodies
- HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HEXIM1 antibody is conjugated to Cy5
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HEXIM1/EDG1
- Isotype
- IgG
- Top Product
- Discover our top product HEXIM1 Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
- Alternative Name
- HEXIM1 (HEXIM1 Products)
- Synonyms
- HEXIM1 antibody, fd44h02 antibody, hexim antibody, wu:fd44h02 antibody, zgc:162976 antibody, CLP1 antibody, EDG1 antibody, HIS1 antibody, MAQ1 antibody, 7330426E13Rik antibody, CLP-1 antibody, Clp1 antibody, Clp-1 antibody, hexamethylene bisacetamide inducible 1 antibody, hexamethylene bis-acetamide inducible 1 antibody, hexamethylene bis-acetamide inducible 1 L homeolog antibody, HEXIM1 antibody, hexim1 antibody, Hexim1 antibody, hexim1.L antibody
- Background
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Synonyms: Cardiac lineage protein 1, CLP 1, CLP1, EDG 1, EDG1, Estrogen down-regulated gene 1 protein, Hexamethylene bis acetamide inducible 1, Hexamethylene bis acetamide inducible protein, Hexamethylene bis acetamide inducible transcript 1, Hexamethylene bis-acetamide-inducible protein 1, HEXI1_HUMAN, HEXIM 1, Hexim1, HEXIM1 protein, HIS 1, HIS1, HMBA inducible, MAQ 1, MAQ1, Menage a quatre 1, Menage a quatre protein 1, Protein HEXIM1.
Background: Hexamethylene bis-acetamide inducible 1 (HEXIM1) and Hexamethylene bis-acetamide inducible 2 (HEXIM2) comprise a family of proteins which inhibit positive transcription elongation factor b (P-TEFb) through association with 7SK. P-TEFb is composed of a catalytic subunit, Cdk9, and either Cyclin T1 or T2 as a regulatory subunit. This complex regulates eukaryotic gene expression at the level of elongation. The C-terminal domains of HEXIM proteins interact directly with each other. Via these domains, HEXIM1 and HEXIM2 form stable homo- and hetero-oligomers, which may aid in the formation of the 7SK small nuclear ribonucleic acid particle. Despite their similar functions, HEXIM1 and HEXIM2 exhibit distinct expression patterns in various established cell lines and human tissues.
- Gene ID
- 10614
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