UBR7 antibody (HRP)

Catalog No. ABIN1421542

This Rabbit Polyclonal antibody specifically detects UBR7 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for UBR7 antibody (HRP) (ABIN1421542)

Target: UBR7 (Ubiquitin Protein Ligase E3 Component N-Recognin 7 (UBR7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBR7 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-UBR7 Antibody (HRP)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UBR7/C14orf130

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for UBR7

Target: UBR7 (Ubiquitin Protein Ligase E3 Component N-Recognin 7 (UBR7))

Alternative Name: C14orf130

Background:

Synonyms: Chromosome 14 open reading frame 130, N recognin 7, Putative E3 ubiquitin-protein ligase UBR7, Ubiquitin protein ligase E3 component n-recognin 7 putative, UBR7, UBR 7, UBR-7, UBR7_HUMAN.

Background: Ubr7 is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.