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CHPT1 antibody (Cy5)

CHPT1 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal Cy5
Catalog No. ABIN1422174
  • Target See all CHPT1 Antibodies
    CHPT1 (Choline Phosphotransferase 1 (CHPT1))
    Reactivity
    Human, Mouse, Rat
    Host
    • 30
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHPT1 antibody is conjugated to Cy5
    Application
    • 30
    • 14
    • 12
    • 12
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CHPT1
    Isotype
    IgG
    Top Product
    Discover our top product CHPT1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CHPT1 (Choline Phosphotransferase 1 (CHPT1))
    Alternative Name
    CHPT1 (CHPT1 Products)
    Synonyms
    CPT antibody, CPT1 antibody, choline phosphotransferase 1 antibody, choline phosphotransferase 1 L homeolog antibody, CHPT1 antibody, chpt1 antibody, Chpt1 antibody, chpt1.L antibody
    Background

    Synonyms: AAPT1-like protein, Cholinephosphotransferase 1, chpt1, CHPT1_HUMAN, Diacylglycerol cholinephosphotransferase 1, hCPT1.

    Background: CHPT1, also known as AAPT1-like protein and Diacylglycerol cholinephosphotransferase 1, is a 406 amino acid multi-pass membrane protein that is localized to the golgi apparatus. By catalyzing the phosphatidylcholine biosynthesis from CDP-choline, it plays an essential role in the formation and maintenance of vesicular membranes. CHPT1 is most abundant in testis, as well as small intestine, heart, colon, spleen and prostate. Expression of CHPT1 is increased in cancerous breast cells as compared to normal breast cell lines and it has been determined that the CHPT1 gene exhibits mutations within the cancerous cells. Interestingly, exposure to mustard gas significantly decreases CHPT1 gene expression and activity, an event that may play an important role in the development of acute respiratory distress syndrome (ARDS). There are two isoforms of CHPT1 that are produced as a result of alternative splicing events.

    Gene ID
    56994
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