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AIDA antibody (Cy3)

AIDA Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal Cy3
Catalog No. ABIN1422617
  • Target See all AIDA Antibodies
    AIDA (Axin Interactor, Dorsalization Associated (AIDA))
    Reactivity
    • 44
    • 19
    • 18
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 40
    • 4
    Rabbit
    Clonality
    • 42
    • 2
    Polyclonal
    Conjugate
    • 18
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIDA antibody is conjugated to Cy3
    Application
    • 38
    • 18
    • 12
    • 3
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf180/AIDA
    Isotype
    IgG
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  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    AIDA (Axin Interactor, Dorsalization Associated (AIDA))
    Alternative Name
    C1orf80 (AIDA Products)
    Synonyms
    C1orf80 antibody, RP11-378J18.7 antibody, 2610208M17Rik antibody, BC004835 antibody, zgc:73327 antibody, AIDA antibody, axin interactor, dorsalization associated antibody, axin interactor, dorsalization associated L homeolog antibody, axin interactor, dorsalization associated S homeolog antibody, AIDA antibody, Aida antibody, aida antibody, aida.L antibody, aida.S antibody
    Background

    Synonyms: dorsalization-associated protein, AIDA, AIDA_HUMAN, Axin interaction partner and dorsalization antagonist, Axin interactor, Axin interactor, dorsalization associated, Chromosome 1 open reading frame 80, UPF0491 protein C1orf80.

    Background: AIDA, also known as C1orf80, is a 306 amino acid protein that belongs to the axin interactor family. Expressed in a variety of tissues, including skeletal muscle and heart, AIDA functions as a ventralizing factor during embryogenesis, disrupting Axin homodimerization and inhibiting Axin-mediated JNK activation. Axin, a scaffold protein, is important for both JNK signaling and the canonical Wnt pathway, two processes that play an essential role in embryonic dorsoventral patterning. Disruption of Axin by AIDA results in the negative regulation of JNK and Wnt signaling, thereby affecting embryonic developmental events. Three isoforms of AIDA exist due to alternative splicing events.

    Gene ID
    439927
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