MMAA antibody (Cy5.5)

Catalog No. ABIN1423561

This Rabbit Polyclonal antibody specifically detects MMAA in WB and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MMAA antibody (Cy5.5) (ABIN1423561)

Target: MMAA (Methylmalonic Aciduria (Cobalamin Deficiency) Type A (MMAA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMAA antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MMAA Antibody (Cy5.5)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MMAA/cblA

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MMAA

Target: MMAA (Methylmalonic Aciduria (Cobalamin Deficiency) Type A (MMAA))

Alternative Name: cblA

Background:

Synonyms: mitochondrial, cblA, MMAA protein, Methylmalonic aciduria cobalamin deficiency cblA type, Methylmalonic aciduria cobalamin deficiency type A, Methylmalonic aciduria type A protein, Methylmalonic aciduria type A protein mitochondrial, MMAA, MMAA_HUMAN.

Background: The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria. [provided by RefSeq, Jul 2008].

Gene ID: 166785

Pathways: Monocarboxylic Acid Catabolic Process