CD235b/GYPB antibody (AA 20-59) (PE)

Catalog No. ABIN1424030

The Rabbit Polyclonal anti-CD235b/GYPB antibody has been validated for FACS. It is suitable to detect CD235b/GYPB in samples from Human.

Quick Overview for CD235b/GYPB antibody (AA 20-59) (PE) (ABIN1424030)

Target: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD235b/GYPB antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-CD235b/GYPB Antibody (PE)

Binding Specificity: AA 20-59

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glycophorin B

Isotype: IgG

Application Details

Application Notes: FCM(1:20-100)

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for CD235b/GYPB

Target: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Alternative Name: Glycophorin B

Background:

Glycophorins A, B and C are sialoglycoproteins of the human erythrocyte membrane, which bear the antigenic determinants for the MN, Ss and Gerbich blood groups, respectively. Glycophorins span the membrane once and present their amino-terminal end to the extracellular surface of the human erythrocyte. The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual. The human Glycophorin A gene maps to chromosome 4q31.21, contains seven exons which are 97 % homologous to Glycophorin B, and encodes a 150 amino acid protein. The human Glycophorin B gene maps to chromosome 4q31.21 and encodes a 91 amino acid protein. The human Glycophorin C gene maps to chromosome 2q14.3 and contains four exons. Glycophorin C transcript can generate two protein isoforms. Isoform 1 includes all 4 exons and encodes the full length 128 amino acid protein. Isoform 2 is missing exon 2 and encodes a 109 amino acid protein, which specifies the Yus subtype of the Gerbich phenotype.

Subcellular location: Extracellular

Synonyms: SS, GPB, MNS, PAS-3, CD235b, GPB.NY, HGpMiX, GpMiIII, HGpMiVI, GYPHe.NY, HGpMiIII, Glycophorin-B, SS-active sialoglycoprotein, Sialoglycoprotein delta, GYPB

Gene ID: 2994

UniProt: P06028