LINGO4 antibody (PE-Cy5)

Catalog No. ABIN1428617

The Rabbit Polyclonal anti-LINGO4 antibody is suitable to detect LINGO4 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for LINGO4 antibody (PE-Cy5) (ABIN1428617)

Target: LINGO4 (Leucine Rich Repeat and Ig Domain Containing 4 (LINGO4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO4 antibody is conjugated to PE-Cy5

Application: Western Blotting (WB)

Product Details anti-LINGO4 Antibody (PE-Cy5)

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LINGO4

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LINGO4

Target: LINGO4 (Leucine Rich Repeat and Ig Domain Containing 4 (LINGO4))

Alternative Name: LINGO4

Background:

Synonyms: Leucine rich repeat and Ig domain containing 4, Leucine rich repeat and immunoglobulin like domain containing nogo receptor interacting protein 4, Leucine rich repeat neuronal protein 6D, LRRN6D, LIGO4_HUMAN.

Background: Lingo-4 is a 593 amino acid single-pass type I membrane protein that contains eleven LRR (leucine-rich) repeats, one Ig-like C2-type (immunoglobulin-like) domain, one LRRCT domain and one LRRNT domain. The gene that encodes Lingo-4 consists of approximately 5,891 bases and maps to human chromosome 1q21.3. Comprising nearly 8 % of the human genome, chromosome 1 spans 260 million base pairs, contains over 3,000 genes and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome.

Molecular Weight: 61kDa