LRRTM4 antibody (PE)

Catalog No. ABIN1428640

This Rabbit Polyclonal antibody specifically detects LRRTM4 . It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LRRTM4 antibody (PE) (ABIN1428640)

Target: LRRTM4 (Leucine Rich Repeat Transmembrane Neuronal 4 (LRRTM4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRTM4 antibody is conjugated to PE

Application: Please inquire

Product Details anti-LRRTM4 Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRRTM4

Isotype: IgG

Application Details

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for LRRTM4

Target: LRRTM4 (Leucine Rich Repeat Transmembrane Neuronal 4 (LRRTM4))

Alternative Name: Lrrtm4

Background:

The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/â^ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development. Localizing predominantly to the nervous system, LRRTM family members are known to exhibit synaptogenic activity. LRRTM4 (leucine-rich repeat transmembrane neuronal protein 4) is a 590 amino acid member of the LRRTM protein family. Expressed in neuronal tissues, LRRTM4 may play a role in the development and maintenance of the vertebrate nervous system. A single-pass type I membrane protein, LRRTM4 contains 10 LRR repeats. LRRTM4 is expressed as two isoforms produced by alternative splicing.

Subcellular location: Extracellular

Synonyms: Leucine rich repeat transmembrane neuronal 4, Leucine rich repeat transmembrane neuronal 4 protein, Leucine rich repeat transmembrane neuronal protein 4, Leucine-rich repeat transmembrane neuronal 4 protein, Leucine-rich repeat transmembrane neuronal protein 4, LRRT4_HUMAN, Lrrtm4.

Pathways: Synaptic Membrane