KCNJ8 antibody (PE)

Catalog No. ABIN1431636

The PE-conjugated Rabbit Polyclonal anti-KCNJ8 antibody (ABIN1431636) specifically detects KCNJ8 in WB, IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for KCNJ8 antibody (PE) (ABIN1431636)

Target: KCNJ8 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ8 antibody is conjugated to PE

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-KCNJ8 Antibody (PE)

Purpose: kir 6.1 Polyclonal Antibody, PE Conjugated

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human kir 6.1

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KCNJ8

Target: KCNJ8 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8))

Alternative Name: Kir 6.1

Background:

Synonyms: KIR6.1, uKATP-1, ATP-sensitive inward rectifier potassium channel 8, Inward rectifier K(+) channel Kir6.1, Potassium channel, inwardly rectifying subfamily J member 8, KCNJ8

Background: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).

Molecular Weight: 47kDa

Gene ID: 3764

UniProt: Q15842