IGSF1 antibody (PE)

Catalog No. ABIN1434897

This anti-IGSF1 antibody is a Rabbit Polyclonal antibody detecting IGSF1 in WB. Suitable for Human, Mouse, Rat, Dog and Pig.

Quick Overview for IGSF1 antibody (PE) (ABIN1434897)

Target: IGSF1 (INHBP) (Inhibin Binding Protein (INHBP))

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGSF1 antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-IGSF1 Antibody (PE)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IGSF1

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IGSF1

Target: IGSF1 (INHBP) (Inhibin Binding Protein (INHBP))

Alternative Name: IGSF1

Background:

Synonyms: PGSF2, IGCD1, IGDC1, Immunoglobulin like domain containing protein 1, Immunoglobulin superfamily member 1, InhBP, Inhibin binding protein, KIAA0364, p120, Pituitary gland specic factor 2, IGSF1_HUMAN.

Background: IGSF1 is a highly glycolylated immunoglobulin domain-containing protein. IGSF1 has been shown to act as a coreceptor in inhibin signaling, however, it does not appear to be a high-affinity inhibin receptor by itself. May reduce or inhibit activin A signaling and is believed to be necessary in the mediation of specific effects of inhibin B on activin-stimulated transcription. IGSF1 has been found to interact with several members of the ACVR family and possibly some members of the BMPR group. There are 3 known isoforms of IGSF1, with 1 and 2 likely being multi-pass membrane proteins. Isoform 3 is believed to be expressed as a secreted form. Expression is high in pancreas, testis and fetal liver, while heart, prostate and small intestine show only moderate expression. IGSF1 may be found at very low levels in brain, muscle, thymus, ovary, colon, fetal lung and fetal kidney. Isoform 3 has been detected in pituitary gland.

Molecular Weight: 144kDa

Gene ID: 3547