RNF130 antibody (PE-Cy5)

Catalog No. ABIN1435189

This Rabbit Polyclonal antibody specifically detects RNF130 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow.

Quick Overview for RNF130 antibody (PE-Cy5) (ABIN1435189)

Target: RNF130 (Ring Finger Protein 130 (RNF130))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF130 antibody is conjugated to PE-Cy5

Application: Western Blotting (WB)

Product Details anti-RNF130 Antibody (PE-Cy5)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF130

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RNF130

Target: RNF130 (Ring Finger Protein 130 (RNF130))

Alternative Name: RNF130

Background:

Synonyms: GOLIATH, 2510042A13Rik, G1 related zinc finger protein, G1rp, G1RZFP, GP antibody MGC117241, MGC138647, MGC99542, R goliath, RING finger protein 130, GOLI_HUMAN.

Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF130 (ring finger protein 130), also known as GP, G1RZFP (G1-related zinc finger protein) or GOLIATH, is a 419 amino acid single-pass type I membrane protein that shares similarity with a Drosophila zinc-finger protein found in mesoderm known as g1. RNF130 contains one PA (protease associated) domain and a single RING-type zinc finger. Implicated in the regulation of growth factor withdrawal-induced apoptosis of myeloid precursor cells, RNF130 is encoded by a gene located on human chromosome 5q35.3 and mouse chromosome 11 B1.3.

Molecular Weight: 46kDa

Gene ID: 55819