RNF130 antibody (AA 200-280)

Catalog No. ABIN7216900

The Rabbit Polyclonal anti-RNF130 antibody is suitable to detect RNF130 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for RNF130 antibody (AA 200-280) (ABIN7216900)

Target: RNF130 (Ring Finger Protein 130 (RNF130))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF130 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RNF130 Antibody

Binding Specificity: AA 200-280

Purpose: Rabbit Anti-RNF130 Polyclonal Antibody

Specificity: RNF130 Polyclonal Antibody detects endogenous levels of RNF130 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human RNF130 at AA range: 200-280

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RNF130

Target: RNF130 (Ring Finger Protein 130 (RNF130))

Alternative Name: RNF130

Background: RNF130, E3 ubiquitin-protein ligase RNF130, Goliath homolog, H-Goliath, RING finger protein 130E3 ubiquitin-protein ligase RNF130 encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants.

Molecular Weight: 36kD

Gene ID: 55819

UniProt: Q86XS8