P-Selectin antibody (APC)

Catalog No. ABIN1449147

This anti-P-Selectin antibody is a Mouse Monoclonal antibody detecting P-Selectin in FACS. Suitable for Human and Primate.

Quick Overview for P-Selectin antibody (APC) (ABIN1449147)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This P-Selectin antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: AK4

Product Details anti-P-Selectin Antibody (APC)

Cross-Reactivity (Details): Species reactivity (tested):Human, Primates

Immunogen: Human platelets

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline (PBS), 15 mM sodium azide, 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE! This products is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store undiluted at 2-8 °C.

Target Details for P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Alternative Name: CD62P / P-Selectin

Background: CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

Gene ID: 6403

NCBI Accession: NP_002996

UniProt: P16109