KPNB1 antibody
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- Target See all KPNB1 Antibodies
- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This KPNB1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects Importin β.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human
- Purification
- Protein G agarose
- Immunogen
- Recombinant full-length mouse importin beta
- Clone
- 1D7
- Isotype
- IgG2a
- Top Product
- Discover our top product KPNB1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Upon receipt, store (in aliqouts) at -20 °C.
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- Target
- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
- Alternative Name
- NTF97 (KPNB1 Products)
- Synonyms
- Afu1g15720 antibody, AO090005001133 antibody, imb1 antibody, impnb antibody, ipo1 antibody, ipob antibody, ntf97 antibody, IMB1 antibody, IPO1 antibody, IPOB antibody, Impnb antibody, NTF97 antibody, AA409963 antibody, importin beta-1 subunit antibody, Importin beta-1 subunit antibody, karyopherin (importin) beta 1 L homeolog antibody, importin beta 1 antibody, karyopherin subunit beta 1 antibody, karyopherin (importin) beta 1 antibody, AFUA_1G15720 antibody, AOR_1_1974174 antibody, Bm1_57540 antibody, PMAA_065830 antibody, AFLA_083750 antibody, TSTA_085870 antibody, BDBG_07509 antibody, MCYG_00039 antibody, kpnb1.L antibody, LOC100533387 antibody, KPNB1 antibody, Kpnb1 antibody
- Background
- Importin ß (karyopherin ß/PTAC97) forms a complex with importin a that is required for classical import of proteins across the nuclear envelope through the nuclear pore complex. Importin a acts as a bridge between the nuclear localization sequence (NLS) and importin ß, while importin ß is the site of initial docking to the pore and is responsible for transport of the target protein into the nucleus. Inside the nucleus, Ran-GTP binds to importin ß, resulting in dissociation of the ternary complex, and importin a and ß are independently recycled back into the cytoplasm. Recently some NLS-containing proteins have been shown to bind directly to importin ß and enter the nucleus in an importin a independent manner.Synonyms: Importin subunit beta-1, Importin-90, KPNB1, Nuclear factor P97
- Molecular Weight
- 96 kDa
- Gene ID
- 3837
- NCBI Accession
- NP_002256
- UniProt
- Q14974
- Pathways
- Protein targeting to Nucleus
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