DLK1 antibody (PE)

Catalog No. ABIN1449215

The Rat Monoclonal anti-DLK1 antibody is suitable to detect DLK1 in samples from Mouse. It has been validated for FACS.

Quick Overview for DLK1 antibody (PE) (ABIN1449215)

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This DLK1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 24-11-14

Product Details anti-DLK1 Antibody (PE)

Specificity: This antibody reacts with Dlk.

Cross-Reactivity (Details): Species reactivity (tested):Mouse

Purification: Protein G Agarose Chromatography of hybridoma supernatant

Immunogen: Pref-1-Fc protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 1 mLPBS, 0.09 % Sodium Azide, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 2-8 °C.

Target Details for DLK1

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Alternative Name: DLK1

Background: Delta like protein (Dlk), also known as Preadipocyte factor-1 (Pref-1) or zona glomerulosa-specific factor (ZOG), is an EGF-like transmembrane protein expressed preadipocytes but not in mature adipocytes. It is highly expressed in fetal liver, the adrenal gland, and placenta, as well as some neuroendocrine tumors and small cell lung carcinomas, where it plays a role in differentiation and proliferation. Dlk positively and negatively regulates adipocyte differentiation via at least four major variants (45-60 kDa) of Dlk generated by alternatively splicing. Constitutive expression of Dlk inhibits adipogenesis, but insulin or insulin like growth factor-1 (IGF-1) can circumvent this inhibition. Regulated processing of Dlk releases a 50 kDa soluble form that was previously characterized as Fetal Antigen-1, a protein involved in pancreatic island cell differentiation.Synonyms: DLK, DLK-1, PREF1, Preadipocyte factor 1, Protein delta homolog 1, pG2

Gene ID: 13386

NCBI Accession: NP_034182

UniProt: Q09163