HNRNPA2B1 antibody

Catalog No. ABIN1449240

Product Details anti-HNRNPA2B1 Antibody

Target: HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This HNRNPA2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificity: This antibody reacts with hnRNP-A2/B1.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Immunogen: Protein fraction extracted from the mitotic chromosome

Clone: C20308

Isotype: IgM

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Upon receipt, store (in aliqouts) at -20 °C.

Target Details for HNRNPA2B1

Target: HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))

Alternative Name: HnRNP-A2/B1 / HNRNPA2B1 (HNRNPA2B1 Products)

Background: The heterogeneous nuclear ribonucleoprotein-A2/B1 (hnRNP-A2/B1) was recently shown to be up-regulated in th e early stage of lung cancer. This protein plays an important role in biogenesis and transport of mRNA. Up-regulation of hnRNP usually precedes morphological differentiation and is considered a good biomarker in the early stages of cancer development. HnRNP-A2/B1 proteins were localized primarily in the nucleus, excluding the nucleolus, although the expression of A2 protein was weaker than that of B1 protein. hnRNP-A2/B1 proteins were apparently expressed in nonmalignant alveolar cells as well as cancer cells, although the expression in alveolar cells was weaker than that of cancer cells.Synonyms: HNRPA2B1, Heterogeneous nuclear ribonucleoproteins A2/B1, hnRNP A2 / hnRNP B1

Molecular Weight: 40 kDa

Gene ID: 3181

NCBI Accession: NP_002128

UniProt: P22626