SUMO2 antibody
Quick Overview for SUMO2 antibody (ABIN1449280)
Target
See all SUMO2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody reacts with SUMO-2/3 (15 kDa) but not react with SUMO-1 (15~17 kDa) on Western blot.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse, Rat
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Purification
- Protein A agarose
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Immunogen
- Recombinant full-length human SUMO-2
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Isotype
- IgG2b
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Upon receipt, store (in aliqouts) at -20 °C.
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- SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
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Alternative Name
- SUMO2
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Background
- Sumoylation, the covalent attachment of a small ubiquitin-like modifier (SUMO) peptide to lysine residues of targeted substrate, has recently emerged as an important mechanism in transcriptional control. In humans and mice, the SUMO family consists of three members, SUMO-1, -2, and -3. SUMO-2 (SMT3A, Sentrin-3) and SUMO-3 (SMT3B, Sentrin-2) are similar (~95 % identical), but less closely related to SUMO-1 (~50 % identical). Whereas many proteins modified by SUMO-1 were identified, many as yet unidentified proteins are modified by SUMO-2/3 after exposure of cells to various stress stimuli.Synonyms: HSMT3, SMT3 homolog 2, SMT3A, SMT3H2, SUMO-3, Sentrin-2, Small ubiquitin-related modifier 2, Smt3A, Ubiquitin-like protein SMT3A
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Gene ID
- 6613
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NCBI Accession
- NP_001005849
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UniProt
- P61956
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Pathways
- Methionine Biosynthetic Process
Target
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