The Mouse Monoclonal anti-KIF11 antibody (Clone 3A1) (ABIN1449288) specifically detects KIF11 in WB and IP.
The antibody is reactive with Human samples.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
Preservative
Without preservative
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Upon receipt, store (in aliqouts) at -20 °C.
Target
KIF11
(Kinesin Family Member 11 (KIF11))
Alternative Name
KIF11
Background
KIF11(Eg5), a member of kinesin superfamily, is a tetrameric motor protein that is phosphorylated specifically during mitosis by cdc2/cyclin B kinase at Thr927. It is essential to forming bipolar spindles needed to divide sister chromatids, inhibition of KIF11 arrests HeLa cells at mitosis with monoaster state.Synonyms: EG5, KIF11, KNSL1, Kinesin-like protein 1, Kinesin-like protein KIF11, Kinesin-like spindle protein HKSP, Kinesin-related motor protein Eg5, TRIP-5, TRIP5, Thyroid receptor-interacting protein 5