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ATG12 antibody (N-Term)

ATG12 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1449610
  • Target See all ATG12 Antibodies
    ATG12 (Autophagy Related 12 (ATG12))
    Binding Specificity
    • 14
    • 8
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-73, N-Term
    Reactivity
    • 62
    • 30
    • 20
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 64
    • 14
    • 1
    Rabbit
    Clonality
    • 61
    • 18
    Polyclonal
    Conjugate
    • 44
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG12 antibody is un-conjugated
    Application
    • 57
    • 36
    • 25
    • 24
    • 12
    • 12
    • 11
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human APG12L (N-term). Other species not tested.
    Purification
    Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
    Immunogen
    KLH conjugated synthetic peptide between 44~73 amino acids from the N-term of Human APG12L Genename: ATG12
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ATG12 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ATG12 (Autophagy Related 12 (ATG12))
    Alternative Name
    ATG12 / APG12 (ATG12 Products)
    Background
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG12L is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.Synonyms: APG12-like, APG12L, Autophagy-related protein 12, Ubiquitin-like protein ATG12
    Molecular Weight
    15113 Da
    Gene ID
    9140
    NCBI Accession
    NP_004698
    Pathways
    Autophagy
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