ALG2 antibody (C-Term)

Catalog No. ABIN1449836

The Rabbit Polyclonal anti-ALG2 antibody is suitable to detect ALG2 in samples from Human, Mouse, Rat, Cow, Dog, Pig and Xenopus laevis. It has been validated for WB.

Quick Overview for ALG2 antibody (C-Term) (ABIN1449836)

Target: ALG2 (Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALG2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALG2 Antibody

Binding Specificity: C-Term

Sequence: QSDLGQYVTF LRSFSDKQKI SLLHSCTCVL YTPSNEHFGI VPLEAMYMQC

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine, Pig, Dog, African clawed frog, ZebrafishSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the C terminal of human ALG2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for ALG2

Target: ALG2 (Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2))

Alternative Name: ALG2

Background: ALG2 is a member of the glycosyltransferase 1 family. It acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).Synonyms: 3-mannosyltransferase ALG2, Alpha-1, Asparagine-linked glycosylation protein 2, GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase

Gene ID: 85365

NCBI Accession: NP_149078