TTYH1 antibody (C-Term)

Catalog No. ABIN1449922

This Rabbit Polyclonal antibody specifically detects TTYH1 in WB, IF and EIA. It exhibits reactivity toward Human.

Quick Overview for TTYH1 antibody (C-Term) (ABIN1449922)

Target: TTYH1 (Tweety Homolog 1 (TTYH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTYH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-TTYH1 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid synthetic peptide near the carboxy terminus of Human TTYH1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TTYH1

Target: TTYH1 (Tweety Homolog 1 (TTYH1))

Alternative Name: TTYH1

Background: TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.Synonyms: Protein tweety homolog 1

Gene ID: 57348

NCBI Accession: NP_001005367