TTYH1 antibody (N-Term)

Catalog No. ABIN2781896

Cited in 1 publication. The Rabbit Polyclonal anti-TTYH1 antibody (ABIN2781896) specifically detects TTYH1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig and Rabbit samples.

Quick Overview for TTYH1 antibody (N-Term) (ABIN2781896)

Target: TTYH1 (Tweety Homolog 1 (TTYH1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTYH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TTYH1 Antibody

Binding Specificity: N-Term

Purpose: TTYH1 Antibody - N-terminal region

Sequence: GAPPGYRPSA WVHLLHQLPR ADFQLRPVPS VFAPQEQEYQ QALLLVAALA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TTYH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TTYH1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44502-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-TTYH1 antibody (ABIN2781896)

Suzuki, Mizuno: "A novel human Cl(-) channel family related to Drosophila flightless locus." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22461-8, (2004) (PubMed).

Target Details for TTYH1

Target: TTYH1 (Tweety Homolog 1 (TTYH1))

Alternative Name: TTYH1

Background:

Background Information: TTYH1 is a member of the tweety family of proteins. Members of this family function as chloride anion channels. TTYH1 functions as a calcium (2+)-independent, volume-sensitive large conductance chloride (-) channel. This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: Tweety homolog 1 (Drosophila)

Alternative Symbols: -

Protein Name: Protein tweety homolog 1

Molecular Weight: 49kDa

Gene ID: 57348

NCBI Accession: NP_065710

UniProt: Q9H313