PLAGL2 antibody (N-Term)

Catalog No. ABIN1449972

The Rabbit Polyclonal anti-PLAGL2 antibody (ABIN1449972) specifically detects PLAGL2 in WB, IF and EIA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PLAGL2 antibody (N-Term) (ABIN1449972)

Target: PLAGL2 (Pleiomorphic Adenoma Gene-Like 2 (PLAGL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAGL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-PLAGL2 Antibody

Binding Specificity: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid synthetic peptide near the amino terminus of Human PLAGL2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for PLAGL2

Target: PLAGL2 (Pleiomorphic Adenoma Gene-Like 2 (PLAGL2))

Alternative Name: PLAGL2

Background: The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.Synonyms: KIAA0198, Pleiomorphic adenoma-like protein 2, Zinc finger protein PLAGL2

Molecular Weight: 55 kDa

Gene ID: 5326

NCBI Accession: NP_002648