Claudin 4 antibody (C-Term)

Catalog No. ABIN1449984

Product Details anti-Claudin 4 Antibody

Target: Claudin 4 (CLDN4)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: CLAUDIN4 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human CLAUDIN4.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for Claudin 4

Target: Claudin 4 (CLDN4)

Alternative Name: Claudin-4 / CLDN4 (CLDN4 Products)

Synonyms: CPE-R antibody, CPER antibody, CPETR antibody, CPETR1 antibody, WBSCR8 antibody, hCPE-R antibody, Cep-r antibody, Cpetr antibody, Cpetr1 antibody, CLDN4 antibody, cper antibody, cpe-r antibody, cpetr antibody, cpetr1 antibody, hcpe-r antibody, wbscr8 antibody, claudin 4 antibody, claudin 4 L homeolog antibody, CLDN4 antibody, Cldn4 antibody, cldn4 antibody, cldn4.L antibody

Background: CLAUDIN4 is an integral membrane protein belonging to the claudin family, a family of cellular adhesion molecules that are components of tight junctions. CLAUDIN4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. The CLAUDIN4 gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. CLAUDIN4 is frequently overexpressed in ovarian and other epithelial cancers.Synonyms: CPE-R, CPE-Receptor, CPER, CPETR1, Clostridium perfringens enterotoxin receptor, WBSCR8, Williams-Beuren syndrome chromosomal region 8 protein

Molecular Weight: 23 kDa

Gene ID: 1364

NCBI Accession: NP_001296

Pathways: Hepatitis C