FOXH1 antibody (N-Term)
Quick Overview for FOXH1 antibody (N-Term) (ABIN1450028)
Target
See all FOXH1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- Rabbit polyclonal FOXH1 antibody was raised against a 19 amino acid peptide near the amino terminus of human FOXH1.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- FOXH1 (Forkhead Box H1 (FOXH1))
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Alternative Name
- FOXH1 / FAST1
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Background
- FOXH1 is a member of the Forkhead-box (FOX) family of transcription factors and is the human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 plays an important role in mediating TGF-beta/activin signals through its interaction with the SMAD2-SMAD4 complex. It is expressed primarily during early development and localizes in the cytoplasm until it forms a complex with the SMAD proteins at which time it translocates to the nucleus to positively or negatively affect gene expression.Synonyms: FAST2, Forkhead activin signal transducer 1, Forkhead activin signal transducer 2, Forkhead box protein H1
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Molecular Weight
- 40 kDa
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Gene ID
- 8928
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NCBI Accession
- NP_003914
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Target
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