PRICKLE4 antibody (N-Term)
Quick Overview for PRICKLE4 antibody (N-Term) (ABIN1450076)
Target
See all PRICKLE4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- 18 amino acid synthetic peptide near the amino terminus of Human PRICKLE4
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PRICKLE4 (Prickle Homolog 4 (PRICKLE4))
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Alternative Name
- PRICKLE4
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Background
- PRICKLE4, also known as over-expressed breast tumor protein (OBTP), is a member of the LIM family of proteins. It possesses two LIM domains as well as a PET domain and is thought to localize to the nucleus. Its expression in multiple malignant tissue differentiations indicate that it may play a role in cancer differentiation. Two other members of the LIM family, PRICKLE1 and PRICKLE2, are thought to function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity, suggesting the PRICKLE4 may play a similar role.Synonyms: C6orf49, NRSF-interacting LIM domain protein 4, OBTP, OEBT, REST, TOMM6
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Gene ID
- 29964
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NCBI Accession
- NP_037529
Target
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