SIK3 antibody (C-Term)

Catalog No. ABIN1450082

The Chicken Polyclonal anti-SIK3 antibody is suitable to detect SIK3 in samples from Human, Mouse and Rat. It has been validated for WB, IF and EIA.

Quick Overview for SIK3 antibody (C-Term) (ABIN1450082)

Target: SIK3 (SIK Family Kinase 3 (SIK3))

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This SIK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-SIK3 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the carboxy terminus of human SIK3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SIK3

Target: SIK3 (SIK Family Kinase 3 (SIK3))

Alternative Name: QSK

Background: Salt-inducible kinase family (SIKs) proteins are thought to have a role in steroidogenesis, adipogenesis or regulation of tumor malignancy. Three members (SIK1, SIK2 and SIK3) in the SIK family have been identified thus far. Their kinase domain sequences are closely homologous to those of AMP-activated protein kinase (AMPK). SIK3 can be phosphorylated by a tumor-suppressor kinase LKB1. It is highly and preferentially expressed in ovarian tumors but not in adenomyosis and leiomyoma and may be a potential diagnostic marker for ovarian cancers.Synonyms: EC=2.7.11.1, KIAA0999, QSK, SIK-3, SIK3, Salt-inducible kinase 3, Serine/threonine-protein kinase QSK

Gene ID: 23387

NCBI Accession: NP_079440