MLIP antibody (C-Term)

Catalog No. ABIN1450122

The Rabbit Polyclonal anti-MLIP antibody (ABIN1450122) specifically detects MLIP in WB, IHC (p), IF and EIA. The antibody is reactive with Human samples.

Quick Overview for MLIP antibody (C-Term) (ABIN1450122)

Target: MLIP (Muscular LMNA-Interacting Protein (MLIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-MLIP Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid synthetic peptide near the carboxy terminus of Human MLIP

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MLIP

Target: MLIP (Muscular LMNA-Interacting Protein (MLIP))

Alternative Name: MLIP

Background: The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodiesSynonyms: C6orf142, Muscle enriched A-type lamin interacting protein

Gene ID: 90523

NCBI Accession: NP_612636