TMEM106A antibody (N-Term)

Catalog No. ABIN1450139

The Rabbit Polyclonal anti-TMEM106A antibody has been validated for WB and IHC (p). It is suitable to detect TMEM106A in samples from Human and Mouse.

Quick Overview for TMEM106A antibody (N-Term) (ABIN1450139)

Target: TMEM106A (Transmembrane Protein 106A (TMEM106A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM106A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TMEM106A Antibody

Binding Specificity: N-Term

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid synthetic peptide near the amino terminus of human TMEM106A

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TMEM106A

Target: TMEM106A (Transmembrane Protein 106A (TMEM106A))

Alternative Name: TMEM106A

Background: Transmembrane protein 106A (TMEM106A) is a single-pass transmembrane protein that is closely related to TMEM106B, a protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual roles of TMEM106A and TMEM106B are still undetermined, however, as TMEM106B is involved in FTLD, it is possible that TMEM106A may also be a risk factor for FTLD.Synonyms: Transmembrane protein 106A

Gene ID: 113277

NCBI Accession: NP_659478