TMEM106A antibody (N-Term)

Catalog No. ABIN6991668

The Rabbit Polyclonal anti-TMEM106A antibody (ABIN6991668) specifically detects TMEM106A in ELISA, WB, IHC (p) and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for TMEM106A antibody (N-Term) (ABIN6991668)

Target: TMEM106A (Transmembrane Protein 106A (TMEM106A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM106A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-TMEM106A Antibody

Binding Specificity: N-Term

Purification: TMEM106A Antibody is affinity chromatography purified via peptide column.

Immunogen: TMEM106A antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human TMEM106A. The immunogen is located within the first 50 amino acids of TMEM106A.

Isotype: IgG

Application Details

Application Notes: TMEM106A antibody can be used for detection of TMEM106A by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMEM106A Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TMEM106A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TMEM106A

Target: TMEM106A (Transmembrane Protein 106A (TMEM106A))

Alternative Name: TMEM106A

Background: TMEM106A Antibody: Transmembrane protein 106A (TMEM106A) is a single-pass transmembrane protein that is closely related to TMEM106B, a protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual roles of TMEM106A and TMEM106B are still undetermined, however, as TMEM106B is involved in FTLD, it is possible that TMEM106A may also be a risk factor for FTLD.

Gene ID: 113277

NCBI Accession: NP_659478

UniProt: Q96A25