PKD2 antibody (pSer812)
Quick Overview for PKD2 antibody (pSer812) (ABIN1450365)
Target
See all PKD2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 778-827, pSer812
-
Purpose
- PKD2 (phospho Ser812) Antibody
-
Specificity
- Phospho-PKD2 (S812) Polyclonal Antibody detects endogenous levels of PKD2S812.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
- The antiserum was produced against synthesized peptide derived from human PKD2 around the phosphorylation site of Ser812. AA range:778-827
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C/1 year
-
Expiry Date
- 12 months
-
-
- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
-
Alternative Name
- PKD2
-
Background
-
Synonyms: PKD2, Polycystin-2, Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystwin, R48321
Background: polycystin 2, transient receptor potential cation channel(PKD2) Homo sapiens This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011],
Gene Name: PKD2
Protein Name: Polycystin-2
-
Molecular Weight
- 96 kDa
-
Gene ID
- 5311
-
OMIM
- 173900
-
UniProt
- Q13563
-
Pathways
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
Target
-