ETV6 antibody (AA 223-272)

Catalog No. ABIN1450746

The Rabbit Polyclonal anti-ETV6 antibody (ABIN1450746) specifically detects ETV6 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ETV6 antibody (AA 223-272) (ABIN1450746)

Target: ETV6 (Ets Variant 6 (ETV6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETV6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ETV6 Antibody

Binding Specificity: AA 223-272

Purpose: TEL Antibody

Specificity: TEL Polyclonal Antibody detects endogenous levels of TEL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Tel. AA range:223-272

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ETV6

Target: ETV6 (Ets Variant 6 (ETV6))

Alternative Name: Tel

Background:

Synonyms: ETV6, TEL, TEL1, Transcription factor ETV6, ETS translocation variant 6, ETS-related protein Tel1, Tel

Background: This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008],

Gene Name: ETV6

Protein Name: Transcription factor ETV6

Molecular Weight: 53 kDa

Gene ID: 2120

OMIM: 131440

UniProt: P41212