SIRT1 antibody (AA 13-62)

Catalog No. ABIN1450758

This anti-SIRT1 antibody is a Rabbit Polyclonal antibody detecting SIRT1 in WB, IHC and ELISA. Suitable for Human and Mouse.

Quick Overview for SIRT1 antibody (AA 13-62) (ABIN1450758)

Target: SIRT1 (Sirtuin 1 (SIRT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SIRT1 Antibody

Binding Specificity: AA 13-62

Specificity:

SirT1 Antibody detects endogenous levels of SirT1.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human SirT1.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for SIRT1

Target: SIRT1 (Sirtuin 1 (SIRT1))

Alternative Name: SirT1

Background:

Synonyms: hSIR2, hSIRT1, NAD-dependent deacetylase sirtuin 1, SIR1, SIR2-like protein 1, SIR2L1, sirtuin 1

NCBI Gene Symbol: SIRT1

Molecular Weight: 81 kDa

Gene ID: 23411

OMIM: 604479

UniProt: Q96EB6

Pathways: MAPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling