VAV3 antibody (AA 139-188)

Catalog No. ABIN1450791

The Rabbit Polyclonal anti-VAV3 antibody (ABIN1450791) specifically detects VAV3 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for VAV3 antibody (AA 139-188) (ABIN1450791)

Target: VAV3 (Vav 3 Oncogene (VAV3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAV3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VAV3 Antibody

Binding Specificity: AA 139-188

Purpose: Vav3 Antibody

Specificity: Vav3 Polyclonal Antibody detects endogenous levels of Vav3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human VAV3. AA range:139-188

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for VAV3

Target: VAV3 (Vav 3 Oncogene (VAV3))

Alternative Name: VAV3

Background:

Synonyms: VAV3, Guanine nucleotide exchange factor VAV3, VAV-3

Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Gene Name: VAV3

Protein Name: Guanine nucleotide exchange factor VAV3

Molecular Weight: 97 kDa

Gene ID: 10451

OMIM: 605541

UniProt: Q9UKW4

Pathways: Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway