GTF3C4 antibody (AA 611-660)

Catalog No. ABIN1450890

The Rabbit Polyclonal anti-GTF3C4 antibody (ABIN1450890) specifically detects GTF3C4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GTF3C4 antibody (AA 611-660) (ABIN1450890)

Target: GTF3C4 (General Transcription Factor IIIC, Polypeptide 4 (GTF3C4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF3C4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GTF3C4 Antibody

Binding Specificity: AA 611-660

Purpose: TFIIIC90 Antibody

Specificity: TFIIIC90 Polyclonal Antibody detects endogenous levels of TFIIIC90 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human TF3C4. AA range:611-660

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GTF3C4

Target: GTF3C4 (General Transcription Factor IIIC, Polypeptide 4 (GTF3C4))

Background:

Synonyms: GTF3C4, General transcription factor 3C polypeptide 4, TF3C-delta, Transcription factor IIIC 90 kDa subunit, TFIIIC 90 kDa subunit, TFIIIC90, Transcription factor IIIC subunit delta

Background: catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the TFIIIC subunit 4 family.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6. Interacts with BRF1, GTF3C1, GTF3C2, GTF3C5, GTF3C6, POLR3C and POLR3F.,

Gene Name: GTF3C4

Protein Name: General transcription factor 3C polypeptide 4

Molecular Weight: 92 kDa

Gene ID: 9329

OMIM: 604892

UniProt: Q9UKN8