ATRX antibody (AA 221-270)

Catalog No. ABIN1450956

The Rabbit Polyclonal anti-ATRX antibody (ABIN1450956) specifically detects ATRX in IHC, ELISA, WB and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for ATRX antibody (AA 221-270) (ABIN1450956)

Target: ATRX (helicase 2, X-linked (ATRX))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATRX antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ATRX Antibody

Binding Specificity: AA 221-270

Purpose: Rad54 Antibody

Specificity: Rad54 Polyclonal Antibody detects endogenous levels of Rad54 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human RAD54L. AA range:221-270

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ATRX

Target: ATRX (helicase 2, X-linked (ATRX))

Alternative Name: RAD54

Background:

Synonyms: RAD54L, RAD54A, DNA repair and recombination protein RAD54-like, RAD54 homolog, hHR54, hRAD54

Background: The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008],

Gene Name: RAD54L

Protein Name: DNA repair and recombination protein RAD54-like

Molecular Weight: 84 kDa

Gene ID: 8438

OMIM: 603615

UniProt: Q92698