DHX8 antibody (AA 391-440)

Catalog No. ABIN1451052

The Rabbit Polyclonal anti-DHX8 antibody (ABIN1451052) specifically detects DHX8 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for DHX8 antibody (AA 391-440) (ABIN1451052)

Target: DHX8 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 8 (DHX8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DHX8 Antibody

Binding Specificity: AA 391-440

Purpose: DDX8 Antibody

Specificity: DDX8 Polyclonal Antibody detects endogenous levels of DDX8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human DHX8. AA range:391-440

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DHX8

Target: DHX8 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 8 (DHX8))

Alternative Name: DHX8

Background:

Synonyms: DHX8, DDX8, ATP-dependent RNA helicase DHX8, DEAH box protein 8, RNA helicase HRH1

Background: This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014],

Gene Name: DHX8

Protein Name: ATP-dependent RNA helicase DHX8

Molecular Weight: 139 kDa

Gene ID: 1659

OMIM: 600396

UniProt: Q14562