Glucuronidase beta antibody (AA 321-370)

Catalog No. ABIN1451070

The Rabbit Polyclonal anti-Glucuronidase beta antibody (ABIN1451070) specifically detects Glucuronidase beta in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Glucuronidase beta antibody (AA 321-370) (ABIN1451070)

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucuronidase beta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Glucuronidase beta Antibody

Binding Specificity: AA 321-370

Purpose: Glucuronidase β Antibody

Specificity: Glucuronidase β Polyclonal Antibody detects endogenous levels of Glucuronidase β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human GUSB. AA range:321-370

Isotype: IgG

Application Details

Application Notes: IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Glucuronidase beta

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Alternative Name: GUSB

Background:

Synonyms: GUSB, Beta-glucuronidase, Beta-G1

Background: This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.[provided by RefSeq, May 2014],

Gene Name: GUSB

Protein Name: Beta-glucuronidase

Molecular Weight: 74 kDa

Gene ID: 2990

OMIM: 236750

UniProt: P08236

Pathways: Glycosaminoglycan Metabolic Process