BMP3 antibody (AA 281-330)

Catalog No. ABIN1451076

The Rabbit Polyclonal anti-BMP3 antibody (ABIN1451076) specifically detects BMP3 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for BMP3 antibody (AA 281-330) (ABIN1451076)

Target: BMP3 (Bone Morphogenetic Protein 3 (BMP3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BMP3 Antibody

Binding Specificity: AA 281-330

Purpose: BMP-3A Antibody

Specificity: BMP-3A Polyclonal Antibody detects endogenous levels of BMP-3A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human BMP3. AA range:281-330

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BMP3

Target: BMP3 (Bone Morphogenetic Protein 3 (BMP3))

Alternative Name: BMP3

Background:

Synonyms: BMP3, BMP3A, Bone morphogenetic protein 3, BMP-3, Bone morphogenetic protein 3A, BMP-3A, Osteogenin

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016],

Gene Name: BMP3

Protein Name: Bone morphogenetic protein 3

Molecular Weight: 53 kDa

Gene ID: 651

OMIM: 112263

UniProt: P12645