RCAN1 antibody (AA 201-250)

Catalog No. ABIN1451085

The Rabbit Polyclonal anti-RCAN1 antibody (ABIN1451085) specifically detects RCAN1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RCAN1 antibody (AA 201-250) (ABIN1451085)

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCAN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RCAN1 Antibody

Binding Specificity: AA 201-250

Purpose: DSCR 1 Antibody

Specificity: DSCR 1 Polyclonal Antibody detects endogenous levels of DSCR 1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human RCAN1. AA range:201-250

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Alternative Name: RCAN1

Background:

Synonyms: RCAN1, ADAPT78, CSP1, DSC1, DSCR1, Calcipressin-1, Adapt78, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Regulator of calcineurin 1

Background: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],

Gene Name: RCAN1

Protein Name: Calcipressin-1

Molecular Weight: 22 kDa

Gene ID: 1827

OMIM: 602917

UniProt: P53805

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development