Calpain 9 antibody (AA 481-530)

Catalog No. ABIN1451100

The Rabbit Polyclonal anti-Calpain 9 antibody (ABIN1451100) specifically detects Calpain 9 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Calpain 9 antibody (AA 481-530) (ABIN1451100)

Target: Calpain 9 (CAPN9)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Calpain 9 Antibody

Binding Specificity: AA 481-530

Purpose: Calpain 9 Antibody

Specificity: Calpain 9 Polyclonal Antibody detects endogenous levels of Calpain 9 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human CAPN9. AA range:481-530

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Calpain 9

Target: Calpain 9 (CAPN9)

Alternative Name: CAPN9

Background:

Synonyms: CAPN9, NCL4, Calpain-9, Digestive tract-specific calpain, New calpain 4, nCL-4, Protein CG36

Background: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress.The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: CAPN9

Protein Name: Calpain-9

Molecular Weight: 79 kDa

Gene ID: 10753

OMIM: 606401

UniProt: O14815