DZIP3 antibody (AA 681-730)

Catalog No. ABIN1451238

The Rabbit Polyclonal anti-DZIP3 antibody (ABIN1451238) specifically detects DZIP3 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DZIP3 antibody (AA 681-730) (ABIN1451238)

Target: DZIP3 (DAZ Interacting Protein 3, Zinc Finger (DZIP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DZIP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-DZIP3 Antibody

Binding Specificity: AA 681-730

Purpose: DZIP3 Antibody

Specificity: DZIP3 Polyclonal Antibody detects endogenous levels of DZIP3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human DZIP3. AA range:681-730

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DZIP3

Target: DZIP3 (DAZ Interacting Protein 3, Zinc Finger (DZIP3))

Alternative Name: DZIP3

Background:

Synonyms: DZIP3, KIAA0675, E3 ubiquitin-protein ligase DZIP3, DAZ-interacting protein 3, RNA-binding ubiquitin ligase of 138 kDa, hRUL138

Background: function:E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.,pathway:Protein modification, protein ubiquitination.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with DAZ proteins.,tissue specificity:Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.,

Gene Name: DZIP3

Protein Name: E3 ubiquitin-protein ligase DZIP3

Molecular Weight: 138 kDa

Gene ID: 9666

OMIM: 608672

UniProt: Q86Y13