HOXD8 antibody (AA 241-290)

Catalog No. ABIN1451295

The Rabbit Polyclonal anti-HOXD8 antibody (ABIN1451295) specifically detects HOXD8 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HOXD8 antibody (AA 241-290) (ABIN1451295)

Target: HOXD8 (Homeobox D8 (HOXD8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXD8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HOXD8 Antibody

Binding Specificity: AA 241-290

Purpose: HoxD8 Antibody

Specificity: HoxD8 Polyclonal Antibody detects endogenous levels of HoxD8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human HOXD8. AA range:241-290

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HOXD8

Target: HOXD8 (Homeobox D8 (HOXD8))

Alternative Name: HOXD8

Background:

Synonyms: HOXD8; HOX4E; Homeobox protein Hox-D8; Homeobox protein Hox-4E; Homeobox protein Hox-5.4

Background: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010],

Gene Name: HOXD8

Protein Name: Homeobox protein Hox-D8

Molecular Weight: 31 kDa

Gene ID: 3234

OMIM: 142985

UniProt: P13378