SLC16A2/MCT8 antibody (AA 112-161)

Catalog No. ABIN1451355

The Rabbit Polyclonal anti-SLC16A2/MCT8 antibody (ABIN1451355) specifically detects SLC16A2/MCT8 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SLC16A2/MCT8 antibody (AA 112-161) (ABIN1451355)

Target: SLC16A2/MCT8 (SLC16A2) (Solute Carrier Family 16 Member 2 (SLC16A2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC16A2/MCT8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SLC16A2/MCT8 Antibody

Binding Specificity: AA 112-161

Purpose: MCT8 Antibody

Specificity: MCT8 Polyclonal Antibody detects endogenous levels of MCT8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human SLC16A2. AA range:112-161

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SLC16A2/MCT8

Target: SLC16A2/MCT8 (SLC16A2) (Solute Carrier Family 16 Member 2 (SLC16A2))

Alternative Name: SLC16A2

Background:

Synonyms: SLC16A2, MCT8, XPCT, Monocarboxylate transporter 8, MCT 8, Monocarboxylate transporter 7, MCT 7, Solute carrier family 16 member 2, X-linked PEST-containing transporter

Background: This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012],

Gene Name: SLC16A2

Protein Name: Monocarboxylate transporter 8

Molecular Weight: 59 kDa

Gene ID: 6567

OMIM: 300095

UniProt: P36021

Pathways: Hormone Transport