SLC22A5 antibody (AA 300-349)

Catalog No. ABIN1451421

The Rabbit Polyclonal anti-SLC22A5 antibody (ABIN1451421) specifically detects SLC22A5 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SLC22A5 antibody (AA 300-349) (ABIN1451421)

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SLC22A5 Antibody

Binding Specificity: AA 300-349

Purpose: OCTN2 Antibody

Specificity: OCTN2 Polyclonal Antibody detects endogenous levels of OCTN2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human SLC22A5. AA range:300-349

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SLC22A5

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Alternative Name: SLC22A5

Background:

Synonyms: SLC22A5, OCTN2, Solute carrier family 22 member 5, High-affinity sodium-dependent carnitine cotransporter, Organic cation/carnitine transporter 2

Background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015],

Gene Name: SLC22A5

Protein Name: Solute carrier family 22 member 5

Molecular Weight: 62 kDa

Gene ID: 6584

OMIM: 212140

UniProt: O76082